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KMID : 1007520220310050617
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Food Science and Biotechnology
2022 Volume.31 No. 5 p.617 ~ p.625
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Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells
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Choi Su-Young
Lee Su-Yeon
Kim Hyung-Gyun
Jeong Jae-Cheon
Batara Don Carlo
Kim Sung-Hak
Cho Jeong-Yong
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Abstract
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Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (
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KEYWORD
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Porphyra dentata, Laver, Shinorine, Porphyra-334, Adipocyte differentiation, Adipogenesis
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